Last updated: Tuesday, 30, November, 2010
Mild eosinophilia is a common finding, particularly in children, and is often transient.
Review clinical findings; follow up FBC, differential WCC, blood film.
For persistent or marked eosinophilia, CRP, immunoglobulin E may be helpful.
Marked eosinophilia can occur.
|Skin disorders||Skin biopsy with IH, if indicated.|
Parasitic infection (with tissue invasion)
Faeces - ova, cysts and parasites.
Harada culture on faeces - consult pathologist.
Strongyloides sp antibodies; Harada culture. This is important to identify in patients on steroids or immunosuppression, who have lived in tropical countries, since they are at risk of hyperinfection syndrome.
Usually defined as a marked eosinophilia (>1.5 x 109/L) for more than 6 months in the presence of a consistent clinical picture.
Biopsy of appropriate tissue, if indicated.
|Bone marrow aspiration and trephine biopsy.|
Pulmonary infiltration with eosinophilia (PIE) including
Skin prick allergen testing especially antigens of Aspergillus sp. Aspergillus precipitins; immunoglobulin E.
See under Aspergillosis.