Glomerulonephritis (GN)

Last updated: Friday, 03, December, 2010
Key InformationAppropriate Tests

Urinalysis, urine protein; urine microscopy (fresh specimen examined for casts and dysmorphic red cells).

Electrolytes, creatinine, urea. e GFR.

Diagnosis is established by renal biopsy with IF, IH and electron microscopy.

The possibility of underlying systemic disease should be considered.




Nephritic syndrome

Nephrotic syndrome


Renal failure


Primary renal disease

  • IgA nephropathy

  •  Membranous GN
  • Minimal change disease
  • Post-infectious GN 

Throat swab, skin lesions - bacterial culture. Antistreptolysin O titre, antideoxyribonuclease B antibodies. C3/C4.

  • Crescentic GN

 Glomerular basement membrane antibodies, antineutrophil cytoplasmic antibodies.

Associated with systemic disease

  • Vasculitis syndromes, especially
See Vasculitis
  • Malignancy

Chronic infection-associated GN