Hodgkin's disease

Last updated: Monday, 13, December, 2010
Key InformationAppropriate Tests
Lymph node or tissue biopsy: excision biopsy preferred over FNAB; FBC, blood film; ESR; bone marrow aspiration and trephine biopsy. See also Lymphoma (Classification)
Presentation

Lymphadenopathy/a>

Pyrexia of unknown origin/a>

Weight loss

Pruritus

Classification

Histological findings and extent of disease (staging) are of importance in defining prognosis and determining appropriate management. 

Review clinical features; FBC; ESR; bilirubin, ALP, AST, ALT, LD. Diagnostic imaging; liver biopsy.

Nodular lymphocyte predominant Hodgkin lymphoma

Classical Hodgkin lymphoma

  • Nodular sclerosis classical Hodgkin lymphoma
  • Lymphocyte-rich classical Hodgkin lymphoma
  • Mixed cellularity classical Hodgkin lymphoma
  • Lymphocyte-depleted classical Hodgkin lymphoma