Hypergammaglobulinaemia
Last updated: Monday, 13, December, 2010
| Causes | Appropriate Tests |
|---|---|
The reference interval for gamma globulin varies with age and between racial groups. See Table 2 Reference intervals for immunoglobulins G, A, M (g/L) Protein (total), albumin; protein electrophoresis, immunoglobulins G, A, M; FBC, blood film; CRP. | |
| Polyclonal | |
Chronic bacterial infection | |
Chronic liver disease, especially
|
See under Hepatitis |
Systematic rheumatic disease, especially | |
Angioimmunoblastic lymphadenopathy | See under Immunoproliferative disorders |
Tropical splenomegaly syndrome | |
| Monoclonal | |
MGUS | See Monoclonal gammopathy of undetermined significance |
Chronic lymphoproliferative disorders | See Lymphoproliferative disorders |
Reference: Undas et al. Homocysteine and thrombosis: from basic science to clinical evidence, Thrombosis and Haemostasis 2005: 1994;907-915 Lewis et al. Meta-analysis of MTHFR 6770-*T polymorphism and coronary heart disease: dose totality of evidence support causal role for homocysteine and preventative potential of folate, BMJ 2005 ; 331: 1053 - 1056 |