Last updated: Thursday, 20, January, 2011
Key InformationAppropriate Tests

Review clinical findings. FBC, blood film, differential WCC.

See Table 4 Reference intervals for leucocyte differential counts

With monocytes showing normal morphology.

Acute or chronic bacterial infection, especially


Hodgkin's disease

Recovery from agranulocytosis 

See Neutropenia

Cytokine administration 

Cytokines (eg, G-CSF, GM-CSF) commonly cause neutrophilia and/or monocytosis.

Chronic idiopathic neutropenia

Splenic atrophy/absence

With abnormal 'monocytoid' cells

Myelodysplasia, especially

Monocyte morphology may be abnormal.

Acute myelomonocytic, monocytic leukaemia 

See Acute leukaemia.