Overdose, drug

Last updated: Friday, 24, December, 2010
PresentationsAppropriate Tests

Plasma concentration of drug(s) is the investigation of choice, if the test is available and confirmation of overdose is required.

Consult pathologist for specimen collection requirements.

If the specific drug is uncertain, or other drug(s) suspected: drugs - toxicological screening - urine may be of value - specify likely drug(s) and the clinical findings considered to be drug related.

Because of the frequency and severity of paracetamol overdose, paracetamol - serum levels should be measured in all patients.

See Paracetemol overdose

Assess organ function, as indicated clinically.

Contact local Poisons Information Centre for specific toxicity information.

See also Anticoagulant monitoring, Poisining

CNS depression/dysfunction

Cardiac arrhythmias

See Arrhythmias

Other organ damage

  • Liver dysfunction¬†

Especially Paracetamol overdose

  • Renal dysfunction

Hypoglycaemia

Electrolyte abnormalities

Vomiting