Last updated: Friday, 24, December, 2010
|Key Information||Appropriate Tests|
Diagnostic approach dictated by clinical features. Consider likely cause(s) in terms of site of abnormality. CSF examination may be indicated.
Lower motor neurone
Nerve root compression
Spinal cord compression
Upper motor neurone (cerebral, spinal cord lesions)
Lesion biopsy, including FNAB, if appropriate.
Lesion biopsy, FNAB if appropriate: pus - microscopy and culture.
Motor neurone disease
Molecular genetics - genetic disorders studies on family members, if the disease is suspected to be familial - consult pathologist.
Inherited degenerative disorders
Enzyme studies or molecular genetics - genetic disorders may be available - consult pathologist.
Subacute combined degeneration of the cord
See Vitamin B12 deficiency.