Peptic ulcer

Last updated: Friday, 24, December, 2010
Key InformationAppropriate Tests

Endoscopic biopsy and/or brushings to exclude neoplasm and to detect Helicobacter pylori.

The organism is detected by histology and the urease test - gastric or duodenal ulcer; culture for susceptibility testing may be indicated in patients with recurrent or non-responsive disease.

Serology for H. pylori is seldom indicated.

The urease test - breath may be useful to monitor effectiveness of therapy.

Presentations

Gastric ulcer

Duodenal ulcer

Stress ulcer

Zollinger-Ellison syndrome

Associations

Helicobacter pylori infection

NSAID

Corticosteroids

Renal failure

Polycythaemia rubra vera

Hyperparathyroidism