Splenomegaly

Last updated: Saturday, 05, February, 2011
CausesAppropriate Tests

Review clinical features, including presence of fever, hepatomegaly, lymphadenopathy.

Conditions designated * are typically associated with hepatomegaly.

FBC, blood film, platelet count, differential WCC.

See also Hypersplenism and Hepatomegaly

Infections

Viral, especially

Bacterial, especially

Parasitic, especially

Immune disorders

SLE

Felty syndrome

Disordered splenic blood flow

Portal hypertension*

Haemolytic anaemia

Autoimmune haemolysis*

Hereditary spherocytosis

Homozygous b thalassaemia*

Haemoglobin H disease*

 

 

 

 

 

See under Thalassaemia

See under Thalassaemia

Infiltrative*

Myeloproliferative disorders*

Lymphoma*

Chronic lymphocytic leukaemia*

Hairy cell leukaemia

Prolymphocytic leukaemia

Amyloidosis*

Lysosomal storage diseases*