Therapeutic drug monitoring
Last updated: Saturday, 14, August, 2010
|Key Information||Appropriate Tests|
Monitoring is of value with drugs whose effect is related to the plasma level, and which have a low therapeutic index.
Anticoagulant drugs are monitored by their effect on coagulation tests; see Anticoagulant monitoring.
Inadequate therapeutic response
|Available tests include|
|Phenytoin, carbamazepine, phenobarbitone, valproate, primidone, clonazepam, sulthiame, ethosuximide, lamotrigine.|
|Digoxin, quinidine, procainamide, lignocaine, amiodarone, mexiletine.|
|Tricyclic antidepressants, lithium.|
|Antibiotic assay; gentamicin, tobramycin, amikacin, vancomycin, flucytosine, chloramphenicol.|
|Theophylline, cyclosporin, methotrexate, tacrolimus.|