Hepatitis E virus (HEV) antibodies - serum

Last updated: Tuesday, 07, August, 2007

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Item Process
Specimen

5-10 mL blood in plain tube.

Method

Immunoassay.

Application

Acute hepatitis in a patient from an endemic area or who has visited an endemic area when tests for other causes of hepatitis are negative.

Endemic areas include India, SE Asia, China, areas of Africa, Mexico.

Rarely, severe acute hepatitis with negative serology for other causes of viral hepatitis in a person who has not visited an endemic area.

Interpretation

Anti-HEV antibodies develop early in the course of the illness.

Reference

Worm HC et al. Microbes Infect 2002; 4: 657-666.