Rickettsia sp antibodies
Last updated: Thursday, 25, March, 2004
MBS Online Search Page: Click here for details
5-10 mL blood in plain tube. Acute and convalescent samples.
Confirmation of a clinical diagnosis of typhus (murine or scrub) or spotted fever (including Queensland tick typhus and Flinders Island spotted fever).
The diagnosis of rickettsial infection is confirmed by a four-fold rise in antibody titre between acute and convalescent samples.
The traditional Weil-Felix test, based on the pattern of serological reactions to Proteus sp, lacks sensitivity and specificity and is no longer recommended.
Graves SR. Pathology 1998; 30: 147-152.
Baird RW et al. J Clin Microbiol 1992; 30: 2896-2602.