Lead - urine
Last updated: Thursday, 18, March, 2004
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| Item | Process |
|---|---|
| Specimen | 24 hour urine collection in a lead-free container with HCl (also lead free) as preservative. |
| Method | Atomic absorption spectrophotometry. |
| Reference Interval | <0.25 µmol/24 hours. |
| Application | Monitoring the effect of chelation therapy in lead poisoning. Lead excretion after EDTA infusion is the preferred investigation for past exposure to lead, if blood lead is normal. |
| Interpretation | Lead excretion >0.25 µmol/24 hours indicates an increased body burden. |
| Reference | Markowitz M. Curr Probl Pediatr 2000; 30(3): 62-70. |