Uterine cervix (cervical) biopsy

Last updated: Friday, 19, March, 2004

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Item Process
Specimen

Punch or excision biopsy, biopsies from electrosurgical excision loop procedure (LEEP) or large loop excision of transformation zone (LLETZ), cone biopsy.

Method

Fixed tissue in 10% buffered formal saline.

Application

Investigation of abnormal smears. 

Diagnosis of HPV and other cervical infections. 

Assessment of epithelial hyperplasia and metaplasia, grading of epithelial dysplasia (CIN), diagnosis of invasive malignancy.

Interpretation

Report by pathologist identifies the nature of the lesion sampled. 

Tumour type, grade and stage are reported for neoplasms.

Reference

Robboy SJ et al. Pathology of the Female Reproductive Tract. Churchill Livingstone 2002.