Beta-2-microglobulin - serum

Last updated: Thursday, 08, April, 2004

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Item Process
Specimen

5 mL blood in plain tube.

Method

Immunoassay.

Reference Interval

<60 years: 0.8-2.5 mg/L
>60 years: 0.8-3.0 mg/L.

Application

Provides a useful indicator of prognosis and can be used to follow disease progression in multiple myeloma.

Limited application in the detection of dialysis amyloidosis and in monitoring glomerular filtration in renal disease.

Interpretation

Levels are correlated with tumour load, and thus prognosis, in multiple myeloma.

Reference

Fassas AB, et al. Leuk Lymphoma 2003; 44(5): 749-58.