Oestradiol - serum

Last updated: Thursday, 15, April, 2004

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Item Process
Specimen

5 mL blood in plain tube

Method

Immunossay.

Reference Interval

Female
Early follicular phase: 100-200 pmol/L
Preovulatory phase: 500-1700 pmol/L
Luteal phase: 500-900 pmol/L
Postmenopausal: 70-200 pmol/L.

Application

Diagnosis of precocious puberty.

Monitoring of oestrogen therapy is only possible if the drug being administered is oestradiol.

Monitoring ovulation induction in in vitro fertilisation.

Assessment of women with suspected hypothalamic or pituitary disease.

Interpretation

Increased levels indicate an endogenous or exogenous source of increased oestradiol.

Reference

Goldfien A and Monroe SE. In: Greenspan FS and Baxter JD eds. Basic and Clinical Endocrinology. 4th ed. Prentice Hall 1994.