Last updated: Friday, 19, March, 2004
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Only performed in specialised laboratories.
IF, EIA, solid phase red cell adherence, flow cytometry, direct and indirect antiglobulin techniques, MAIPA.
Platelet aggregation for heparin-dependent antibodies (HIT).
Variously used to demonstrate platelet autoantibodies, drug-dependent antibodies, alloantibodies.
It is sometimes used in the investigation of immune thrombocytopenias: ITP, drug-induced thrombocytopenia (including HIT), post-transfusion purpura and neonatal thrombocytopenia.
Investigation of refractoriness to platelet transfusion.
See also Heparin-dependent platelet antibodies.
Kaplan C et al. Transf Med 1992; 2: 265-271.