Urea - urine

Last updated: Wednesday, 31, March, 2004

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Item Process
Specimen

Random or 24 hour urine collection.

Method

Spectrophotometry.

Reference Interval

420-720 mmol/24 hours.

Application

Urine urea is only occasionally of value in the assessment of nitrogen balance in patients receiving parenteral nutrition, or in selected patients with non-oliguric acute or chronic renal failure.

Urine urea may also be of value on a random specimen, in the presence of oliguria, to assess renal function.

Interpretation

Urea excretion is largely dependent on protein intake, tissue breakdown and renal function.

Reference

Eckfeldt J et al. Clin Chem 1982; 28: 1500-1502.