Legionella pneumophila serogroup 1 antigen - urine
Last updated: Tuesday, 07, August, 2007
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10 ml urine.
A rapid card test is also available but is not as sensitive as EIA.
Investigation of pneumonia possibly due to infection with Legionella pneumophila.
The test has good sensitivity and specificity for Legionella pneumophila serogroup 1 only.
It will be negative in cases due to infection with other serogroups of Legionella pneumophila or other species.
The proportion of cases of legionella pneumonia due to Legionella pneumophila serogroup 1 varies from 40% to 70% in different regions.
The test is usually positive when patients present with clinical pneumonia and may remain positive for weeks following clinical resolution.
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Sopena N et al. Eur J Clin Microbiol Infect Dis 2002; 21: 845-848.