TSH receptor antibodies
Last updated: Wednesday, 31, March, 2004
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| Item | Process |
|---|---|
| Specimen | 5 mL blood in plain tube. |
| Method | Immunoassay, cell stimulation assay. |
| Reference Interval | Method dependent. |
| Application | Limited role in diagnosis of Graves’ disease and Graves' opthalmopathy. Used to predict fetal complications in pregnant patients. This test has superseded the insensitive LATS test. |
| Interpretation | Present in 80% of patients with Graves’ disease. Disappearance with treatment is reported to be correlated with a decreased likelihood of relapse although its predictive significance remains unclear. |
| Reference | Saravanan P et al. Endocrinol Metab Clin North Am 2001; 30(2): 315-337. |