TSH receptor antibodies

Last updated: Wednesday, 31, March, 2004

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Item Process

5 mL blood in plain tube.


Immunoassay, cell stimulation assay.

Reference Interval

Method dependent.


Limited role in diagnosis of Graves’ disease and Graves' opthalmopathy.

Used to predict fetal complications in pregnant patients.

This test has superseded the insensitive LATS test.


Present in 80% of patients with Graves’ disease.

Disappearance with treatment is reported to be correlated with a decreased likelihood of relapse although its predictive significance remains unclear.


Saravanan P et al. Endocrinol Metab Clin North Am 2001; 30(2): 315-337.