Carbohydrate-deficient transferrin - serum
Last updated: Thursday, 08, April, 2004
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5 mL blood in plain tube.
| Reference Interval|
Diagnosis of alcoholism.
Diagnosis of carbohydrate-deficient glycoprotein syndromes (characterised by psychomotor retardation, abnormal adipose tissue distribution, skeletal abnormalities).
This is the most reliable laboratory method for the diagnosis of alcoholism, in cases where the usual laboratory features (eg, increased GGT, red cell macrocytosis) are unnhelpful.
Patients with a genetic carbohydrate-deficient glycoprotein syndrome show decreased levels and abnormal structure of a number of plasma glycoproteins, including transferrin, haptoglobin, thyroxine-binding globulin, antithrombin III and protein C.
Sharpe PC. Ann Clin Biochem 2001; 38: 652-664.