C-Peptide - serum
Last updated: Monday, 06, August, 2007
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5 mL blood in plain tube.
| Reference Interval|
Fasting: 0.8-1.9 µg/L.
To assess pancreatic beta cell function and to distinguish type 1 from type 2 diabetes.
Investigation of hypoglycaemia thought to be due to hyperinsulinism, particularly if surreptitious use of insulin is suspected.
Pancreatic beta cells secrete C-peptide with insulin, so levels decline with beta cell failure.
Inappropriately high levels of insulin and C-peptide during hypoglycaemia indicate endogenous hyperinsulinism.
Inappropriately high levels of insulin with low C-peptide during hypoglycaemia indicate exogenous hyperinsulinism.