Creatinine clearance - Cockcroft and Gault
Last updated: Thursday, 25, March, 2010
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Derived from Serum creatinine measurement; see Creatinine - urine Plasma.
The patient should not eat meat at the meal immediately prior to, or during, the procedure.
| Reference Interval|
Normal > 70 mL/min in a young adult. Typically falling approx 0.5 mL/min per year at ages over 30 years.
The Cockcroft and Gault formula for creatinine clearance is recommended as an estimate of glomerular filtration rate (GFR) for assisting with drug dosing decisions in renal impairment. Normalisation for body surface area is not indicated for drug dosing decisions.
Advice on levels to adjust drug doses available in drug reference sources.
Australian Medicines Handbook