pH - urine

Last updated: Sunday, 21, March, 2004

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Item Process
Specimen

Freshly voided, random urine specimen without preservative.

Method

Hydrogen ion electrode or reagent strip.

See also Urinalysis.

Reference Interval

Physiological range is 4.5-8.0.

Application

Investigation of renal tubular acidosis and monitoring urine pH for other reasons (eg, alkali therapy in cystinuria).

Interpretation

In general, urine pH reflects the pH of the blood.

In distal renal tubular acidosis the urine pH is >5.3 during metabolic acidosis, whereas in normals, or in patients with proximal renal tubular acidosis, urine pH is <5.3 during metabolic acidosis.

Acid urine is produced in metabolic alkalosis with potassium depletion, eg, in pyloric stenosis.

Reference

Roth KS and Chan JC. Clin Pediatr 2001; 40(10): 533-543.