Porphobilinogen deaminase - red cell
Last updated: Thursday, 25, March, 2004
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| Item | Process |
|---|---|
| Specimen | 5 ml blood in lithium heparin tube. |
| Method | Spectrophotometry. |
| Reference Interval | Varies with method: generally 500-800 mU/L. |
| Application | Confirmation of acute intermittent porphyria and diagnosis of asymptomatic family members. |
| Interpretation | Levels are usually decreased by up to 50% in patients with acute intermittent porphyria. However, some patients may have values within the reference interval. Not all persons with the genetic defect have a history of clinical disease. |
| Reference | Lecha M et al. Dermatol Ther. 2003; 16(1): 65-72. |