Skeletal muscle antibodies - serum

Last updated: Friday, 26, March, 2004

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Item Process
Specimen

5 mL blood in plain tube.

Method

Indirect IF.

Reference Interval

Not detected.

Application

Assessment of patients with documented myasthenia gravis; detected in 40% of affected subjects, but in over 90% of those with thymoma.

Acetylcholine receptor antibodies should also be requested.

Interpretation

A positive result indicates that the possibility of thymoma should be actively investigated.

Reference

Skeie G. Annals of the New York Academy of Science  2003; 998: 343-350.