Homovanillate (HVA) - urine
Last updated: Wednesday, 31, March, 2004
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| Item | Process |
|---|---|
| Specimen | Random urine collection. |
| Method | HPLC (creatinine is assayed also, and the result expressed as a ratio, HVA/creatinine). |
| Reference Interval | Depends on age - consult pathologist. |
| Application | Diagnosis and monitoring of neuroblastoma and ganglioneuroma. |
| Interpretation | Levels are increased in most but not all of these tumours. See also Catecholamines - urine and HMMA - urine. |
| Reference | O’Meara AO et al. Acta Paediatr 1994; 83: 88-92. Goldstein DS et al. J Pharmacol Exp Ther 2003; 305(3): 800-811. |