DNA antibodies - serum

Last updated: Thursday, 15, April, 2004

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Item Process
Specimen

5 mL blood in plain tube.

Method

Immunoassay.

Reference Interval

Method dependent - consult pathologist.

Commonly <5 IU/mL.

Application

For confirmation of diagnosis or monitoring of SLE. Sensitivity approximately 70%.

Interpretation

High levels are strongly suggestive of active SLE, particularly with renal involvement.

Lesser elevations may be found occasionally in other autoimmune disorders.

Reference

Gill J et al. Am Fam Physician 2003; 68(11): 2179-2186.