Lipoprotein electrophoresis - plasma or serum
Last updated: Monday, 22, March, 2004
MBS Online Search Page: Click here for details
5 mL blood in EDTA or plain tube taken after a fast of at least 12 hours.
Usually agarose gel electrophoresis with staining for lipids.
| Reference Interval||Qualitative test.|
Investigation of patients with fasting triglyceride levels >4.0 mmol/L, to determine whether they have a type I, IIb, III, IV or V pattern. The test is not needed under other circumstances (eg isolated hypercholesterolaemia) to assess a lipoprotein abnormality. The main importance of the test is the diagnosis of patients with a type III pattern (dysbetalipoproteinaemia) who are at marked risk of premature vascular disease and xanthomata. This diagnosis should be confirmed by apoE genotyping or phenotyping, see Apolipoproteins.
Increased band Patterns
Beta and pre-beta IIb
Broad beta III
Pre-beta and chylomicrons V
Fredrickson DS. Circulation 1975; 51: 209-211.